Key Publications
Possible neuroprotective effects of sulfonylureas in diabetic patients with acute ischemic stroke.
Silver FL, Fang J, Robertson AC, Casaubon L, Kapral MK.
2009 International Stroke Conference. Poster.
De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury.
Gerzanich V, Woo SK, Vennekens R, Tsymbalyuk O, Ivanova S, Ivanov A, Geng Z, Chen Z, Nilius B, Flockerzi V, Freichel M, Simard JM.
Nat Med. 2009 Feb;15(2):185-91. Epub 2009 Jan 25.
Simard JM, Yurovsky V, Tsymbalyuk N, Melnichenko L, Ivanova S, Gerzanich V.
Stroke. 2009 Feb;40(2):604-9. Epub 2008 Nov 20.
Simard JM, Geng Z, Woo SK, Ivanova S, Tosun C, Melnichenko L, Gerzanich V.
J Cereb Blood Flow Metab. 2009 Feb;29(2):317-30. Epub 2008 Oct 15.
Sulfonylurea receptor 1 in the germinal matrix of premature infants.
Simard JM, Castellani RJ, Ivanova S, Koltz MT, Gerzanich V.
Pediatr Res. 2008 Dec;64(6):648-52.
Drugs acting on SUR1 to treat CNS ischemia and trauma.
Simard JM, Woo SK, Bhatta S, Gerzanich V.
Curr Opin Pharmacol. 2008 Feb;8(1):42-9. Epub 2007 Nov 26.
Potential impact of sulfonylureas in the outcome of type 2 diabetic patients with ischemic stroke.
Arboix A.
Stroke. 2007 Sep;38(9):2413-4. Epub 2007 Aug 2. No abstract available.
Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke.
Kunte H, Schmidt S, Eliasziw M, del Zoppo GJ, Simard JM, Masuhr F, Weih M, Dirnagl U.
Stroke. 2007 Sep;38(9):2526-30. Epub 2007 Aug 2.
Simard JM, Tsymbalyuk O, Ivanov A, Ivanova S, Bhatta S, Geng Z, Woo SK, Gerzanich V.
J Clin Invest. 2007 Aug;117(8):2105-13.
Cytotoxic edema: mechanisms of pathological cell swelling.
Liang D, Bhatta S, Gerzanich V, Simard JM.
Neurosurg Focus. 2007 May 15;22(5):E2. Review.
Non-selective cation channels, transient receptor potential channels and ischemic stroke.
Simard JM, Tarasov KV, Gerzanich V.
Biochim Biophys Acta. 2007 Aug;1772(8):947-57. Epub 2007 Mar 19. Review
Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications.
Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V.
Lancet Neurol. 2007 Mar;6(3):258-68. Review.
Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke.
Simard JM, Chen M, Tarasov KV, Bhatta S, Ivanova S, Melnitchenko L, Tsymbalyuk N, West GA, Gerzanich V.
Nat Med. 2006 Apr;12(4):433-40. Epub 2006 Mar 19.