Independent evaluation of the effects of glibenclamide on reducing progressive hemorrhagic necrosis after cervical spinal cord injury.
Popovich PG, Lemeshow S, Gensel JC, Tovar CA.
Exp Neurol. 2010 Dec 9.
http://www.ncbi.nlm.nih.gov/pubmed/21145891

Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury.
Patel AD, Gerzanich V, Geng Z, Simard JM.
J Neuropathol Exp Neurol. 2010 Dec;69(12):1177-90.
http://www.ncbi.nlm.nih.gov/pubmed/21107131

Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma.
Simard JM, Woo SK, Norenberg MD, Tosun C, Chen Z, Ivanova S, Tsymbalyuk O, Bryan J, Landsman D, Gerzanich V.
Sci Transl Med. 2010 Apr 21;2(28):28ra29.
http://www.ncbi.nlm.nih.gov/pubmed/20410530

Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke.
Simard JM, Tsymbalyuk N, Tsymbalyuk O, Ivanova S, Yurovsky V, Gerzanich V.
Stroke. 2010 Mar;41(3):531-7.
http://www.ncbi.nlm.nih.gov/pubmed/20093633

Molecular mechanisms of microvascular failure in central nervous system injury--synergistic roles of NKCC1 and SUR1/TRPM4.
Simard JM, Kahle KT, Gerzanich V.
J Neurosurg. 2010 Sep;113(3):622-9. Review.
http://www.ncbi.nlm.nih.gov/pubmed/20035575

Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion.
Simard JM, Kilbourne M, Tsymbalyuk O, Tosun C, Caridi J, Ivanova S, Keledjian K, Bochicchio G, Gerzanich V.
J Neurotrauma. 2009 Dec;26(12):2257-67.
http://www.ncbi.nlm.nih.gov/pubmed/19604096

Glibenclamide improves neurological function in neonatal hypoxia-ischemia in rats.
Zhou Y, Fathali N, Lekic T, Tang J, Zhang JH.
Brain Res. 2009 May 13;1270:131-9.
http://www.ncbi.nlm.nih.gov/pubmed/19306849

Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke.
Simard JM, Yurovsky V, Tsymbalyuk N, Melnichenko L, Ivanova S, Gerzanich V.
Stroke. 2009 Feb;40(2):604-9.
http://www.ncbi.nlm.nih.gov/pubmed/19023097

Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.
Simard JM, Geng Z, Woo SK, Ivanova S, Tosun C, Melnichenko L, Gerzanich V.
J Cereb Blood Flow Metab. 2009 Feb;29(2):317-30.
http://www.ncbi.nlm.nih.gov/pubmed/18854840

Sulfonylurea receptor 1 in the germinal matrix of premature infants.
Simard JM, Castellani RJ, Ivanova S, Koltz MT, Gerzanich V.
Pediatr Res. 2008 Dec;64(6):648-52.
http://www.ncbi.nlm.nih.gov/pubmed/18679166

Drugs acting on SUR1 to treat CNS ischemia and trauma.
Simard JM, Woo SK, Bhatta S, Gerzanich V.
Curr Opin Pharmacol. 2008 Feb;8(1):42-9.
http://www.ncbi.nlm.nih.gov/pubmed/18032110

The blockade of K(+)-ATP channels has neuroprotective effects in an in vitro model of brain ischemia.
Nisticò R, Piccirilli S, Sebastianelli L, Nisticò G, Bernardi G, Mercuri NB.
Int Rev Neurobiol. 2007;82:383-95.
http://www.ncbi.nlm.nih.gov/pubmed/17678973

Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke.
Kunte H, Schmidt S, Eliasziw M, del Zoppo GJ, Simard JM, Masuhr F, Weih M, Dirnagl U.
Stroke. 2007 Sep;38(9):2526-30.
http://www.ncbi.nlm.nih.gov/pubmed/17673715

Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury.
Simard JM, Tsymbalyuk O, Ivanov A, Ivanova S, Bhatta S, Geng Z, Woo SK, Gerzanich V.
J Clin Invest. 2007 Aug;117(8):2105-13.
http://www.ncbi.nlm.nih.gov/pubmed/17657312

Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke.
Simard JM, Chen M, Tarasov KV, Bhatta S, Ivanova S, Melnitchenko L, Tsymbalyuk N, West GA, Gerzanich V.
Nat Med. 2006 Apr;12(4):433-40.
http://www.ncbi.nlm.nih.gov/pubmed/16550187

Regulation by sulfanylurea receptor type 1 of a non-selective cation channel involved in cytotoxic edema of reactive astrocytes.
Simard JM, Chen M.
J Neurosurg Anesthesiol. 2004 Jan;16(1):98-9.
http://www.ncbi.nlm.nih.gov/pubmed/14676579

Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.
Chen M, Dong Y, Simard JM.
J Neurosci. 2003 Sep 17;23(24):8568-77.
http://www.ncbi.nlm.nih.gov/pubmed/13679426